QUES TION 12 1 points Save Answ The Notch receptor also contains a series of EGF

Question

QUES TION 12 1 points Save Answ The Notch receptor also contains a series of EGF-like repeats. I have been doing my homework and reading about EGF repeats. Integrins and laminins also contain EGF like repeats. Integrins and laminins are static structural proteins and not enzymes. Integrins are transmembrane proteins on animal cells that interactbind laminins. Laminins make up the mortar between cells along with collagen. So integrins and lamins with collagen hold cells in their place like glue. Repeats are often found in very different protein families that are often unrelated in biological function and in the remainder of the protein fold. This can be because the repeating fold forms a biochemically functional unit with a similar molecular role although the proteins are involved in separate processes and not closely related by molecular evolution. What might be true based upon this knowledge? Pick ALL that apply A EGF-like repeats are involved in protein-protein interactions OB EGF-ike repeats are involved in quarternary complexes C. Notch and Delta are involved in holding cells to the extracellular matrix, le, a part of the mortar. D.EGF repeats have no role in protein interactions E EGF repeats are frequently the position of an enzyme's active site. EGF ropoats are frequently the position of an enzyme's active sito. EGF-like repeats on separate proteins may interact together.

Explanation / Answer

Ans-

A. EGF like repeats are involved in protein-protein interactions.

E. EGF repeats are frequently the position of an enzyme's active site.

F. EGF-like repeats on separate proteins may interact together.

Epidermal growth factor (EGF) like repeats are distributed among extracellular proteins which associated with cell adhesion, receptor-ligand interactions, extracellular matrix structure, determination of cell fate, and blood coagulation. They are small protein motifs found as tandem repeats. They are also involved in protein-protein interactions.

Related Questions

Navigate

• Browse (All)
• Browse Q
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.