Refer to Figure 14-18, 19; Lehninger A) The names of the enzyme, cofactor, subst

Question

Refer to Figure 14-18, 19; Lehninger A) The names of the enzyme, cofactor, substrate, product, and pathway are: enzyme Fiotinyl covalently bound cofactorbiotin bitin -thy bound cofactor substrate that comes from glycolysis (no formulas; only single word answer) product that continues through pathway (no formulas; only single word answer) pathway B) Which of the following are true about pyruvate carboxylase? The active site lysine has 2 biotin attached Two biotin-bound CO2 are reacted with pyruvate and two CO2 are released. ATP donates a phosphate group to the enzyme that is released later in the catalytic cycle A single biotin-Lys "arm" binds CO2, moves to site 2, and releases CO2 to react with pyruvate. A single biotin-Lys "arm" moves from catalytic site 1 to catalytic site 2.

Explanation / Answer

A) Substrate that comes from glycolysis-Pyruvate or sometimes Lactate(in anaerobic condition)

Product that continues through pathway-Oxaloacetate,which later transform into Phosphoenol Pyruvate(PEP)

Pathway-Gluconeogenesis

B) Option 4 is true about the enzyme Pyruvate Carboxylase which states that- a single biotin-lys 'arm' binds CO2,moves to site 2 and releases CO2 to react with pyruvate.

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