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2. 150 patients with Crohn\'s disease are given an experimental treatment in whi

ID: 187232 • Letter: 2

Question

2. 150 patients with Crohn's disease are given an experimental treatment in which they all drink "cocktails" containing thousands of pinworm eggs. Within one week, 72% of the patients report a reduction in their abdominal pain. Fill in the following table. Is there a control treatment (and, if so, what is it? | Is there any accounting for individual variation? Is there repetition in the experiment? What, if any, confounding variables are not addressed in the experiment? Can we say with some confidence that ingesting pinworm eggs is an effective treatment for the symptoms of Crohn's disease?

Explanation / Answer

2.

Is there a control treatment : No because all the 150 participants were given the cocktails with thousands of pinworn eggs.

Is there any accounting for individual variation:No, because there are many replicates i.e 150 patients had Crohn's disease and all drank the cocktail with thousands of pinworm eggs.

Is there repetition in the experiment:Yes,many patients(replicas are used).

What if any confounding variables are not addressed in the experiment?Confounding variables could be firstly ,the number of pinworm eggss like how many thousands of pinworm eggs has to be known and secondly the extent of abdominal pain in the patients has to be known without which the exact association between pinworm eggs and reduction in abdominal pain would become spurious.

No we cannot say with some confidence that ingesting pinworm eggs is an effective treatment for the symptoms of Crohn's disease because: