Nathan Ruta - A Find = 9. Replace Select - LC Ba Copy Paste W R 5- 6 - 7 - . PS2

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Nathan Ruta - A Find = 9. Replace Select - LC Ba Copy Paste W R 5- 6 - 7 - . PS2 for Canvas (Z) - Word FILE HOME INSERIDESIGN PAGE LAYOUT REFERENCES MAILINGS REVIEW VIEW X Cut Arial • 12 A A A A 2-E-' . 11 I A bC Aa Bbcc bccD A C D Abcci H Format Pieter Brues X, X A. 2-A. E = = = =, O. , 1 Normal 1 No Spac... Heading1 Heading 2 Title Subtitle Subtle Em... Emphasis Intense E. Strong Quote pouard Paragraph Sly es Question 2. (7 pts). The table includes some types of sequences of nucleic acid (DNA or RNA) observed in eukaryotic nuclear chromosomes, protein-coding genes and RNA transcripts of such genes (ies pre- and mRNA). Use the numbers assigned to each type of sequence to answer the parts below. Use all numbers you need to give a COMPLETE answer to each question. 1. TATA box CAAT box 13. exon centromere 14. Lagging strand 2. Translation start point | 3'UTR or trailer sequence 4. I enhancer 5. telomere Poly (A) site 5' UTR or leader sequence | 10.GC box 11. intron 12. Poly (A) tail 15. Transcription start | site 16. Okazaki fragment 17. promoter 18. Leading strand a. (0.5 pts). replication. The DNA strand that is continuously copied during DNA b. (3 pt). Types of sequences that you would NOT expect to observe in the mature mRNA of a typical protein-coding eukaryotic nuclear gene. This sequence is often observed far upstream of the GC box. c. (0.5 pt). d. (0.5 pt). This sequence is spliced from the pre-mRNA. e. (1 pt). A transcription factor initially binds at this sequence to initiate transcription, f. (0.5 pt). After the "Transcription start point", usually the first sequence to get transcribed into premature-mRNA. g. (1 pt). In the mature mRNA, the sequence for the "Translation start point" would be located between and adjacent to these two sequences. PAGE 10- 2 395 WCRIS E * 7:24 PM = 0 Type here to search o o á e o O wa A - 16 12 2018

Explanation / Answer

In replication of DNA one strand is continuously replicated called leading strand and the other one is discontinuously replicated called lagging strand. In matured eukaryotic messenger RNA we will find only exons joined together between 5l UTR , 5l-cap and 3l UTR and 3l poly A tail. Usually enhancer will be to the upstream of promoter and all these TATA box ,CAAT box and GC box are components of promoter Precursor RNA is combination of introns, the non coding regions and exons, the coding regions, so introns are spliced from pre mature m-RNA. Transcription factor usually binds to the promoter region along with RNA polymerase II . 18 1 ,4 ,7 ,10 ,11, 17 4 11 17 1 9 & 3

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