6, ( 1pt) Two mothers give birth to sons on the same day at a busy hospital. The

Question

6, ( 1pt) Two mothers give birth to sons on the same day at a busy hospital. The son of Mother #1 is afflicted with hemophilia (X-linked recessive). Neither parent has the disease. Mother #2 has a son that does not have hemophilia, despite the fact that the father has hemophilia. Couple #1 is convinced that the hospital mixed up the two newborms, and that they were switched at birth. As a genetic counsclor, you are called to investigate. What information can you provide the hospital concerning the allegation? Is there evidence that they were indeed switched? 7. (2pts) The maternal-effect mutation bicoid (bed) is recessive. In the absence of the bicoid protein product, embryogenesis is not completed. Consider a cross between a female heterozygous for the bicoid mutation, and a homozygous recessive male. a) How is it possible for a male homozygous for the mutation to exist? b) Predict the outcome (normal vs. failed embryogenesis) in the F generation of the cross described, as well as the genotypic ratio expected in the progeny 8. (0.5pt) With incomplete dominance, a likely ratio resulting from a monohybrid cross would be A) 1:2 B) 1:2:2:4 D) 9:3:3:1 E) 3:1

Explanation / Answer

6. Haemophilia is X- linked ressesive disorder, anf it can only be transfer from mother to boy child because father gives only Y chromosome but X chromosome comes from maternal end.

If, mother 1 has haemophilic son then the mother must be a carrier for this disorder, and for mother 2 if the son is not haemophilic it means that mother is not carrier for this order, no concern whether the father is haemophilic or not.

So to confirm the switch mother 1 and 2 both should go for haemophilic test to show which mother is carrier

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