QUESTION 4 a. In mice, the dominant allele Gs of the X-linked gene Greasy produc

Question

QUESTION 4

a. In mice, the dominant allele Gs of the X-linked gene Greasy produces shiny fur, while the recessive wild type Gs+ produces normal fur. The dominant allele Bhd of the X-linked Broadhead gene causes skeletal abnormalities, including broad heads and snouts, while the recessive wild-type Bhd+ allele produces normal skeletons. Female mice heterozygous for both genes were mated to wild tpe males. Of the 100 male offspring scored in this cross, 49 had shiny fur, 48 had skeletal abnormalities, 2 had shiny fur and skeletal abnormalities, and 1 was wild type. What is the genotype of the heterozygous female?

Gs/Gs+; Bhd/Bhd+

Gs Bhd/Gs+ Bhd+

Gs Bhd+/Gs+ Bhd

there’s not enough data to tell

b. Based the data from Question 4, what is the RF value for these two genes?

0.5

0.03

0.015

0.02 for Gs and 0.01 for Bhd

you can’t tell because only males were scored

Please explain your answer. Thank you!

Gs/Gs+; Bhd/Bhd+

Gs Bhd/Gs+ Bhd+

Gs Bhd+/Gs+ Bhd

there’s not enough data to tell

Explanation / Answer

A) Gs Bhd/Gs+ Bhd+ is the genotype of the heterozygous female

B)

Gs Bhd+/Gs+ BhdX Gs+ Bhd+/Y 51 Gs Bhd+ : 48 Gs+ Bhd : 2 Gs Bhd : 1 Gs+ Bhd+

The distance between these two genes RF=(2+1)/100=0.03=3mu

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