What is the MOST IMPORTANT difference between excision and recombination repair?
ID: 191516 • Letter: W
Question
What is the MOST IMPORTANT difference between excision and recombination repair? O In excision repair, a section of dsDNA is removed, but in recombination repair, ssDNA is removed. In excision repair, ssDNA is removed, but in recombination repair, a section of dsDNA is removed. O In excision repair, the damaged DNA is removed and DNA polymerase fills the gap, but in recombination repair, the damaged DNA is removed and the old complementary strand is used to fill the gap. In exc original form without removing it. ision repair, the damaged DNA is removed, but in recombination repair, the damaged DNA is converted back into itsExplanation / Answer
1) Option 4 is the correct answer.
The most important difference between excision and recombination repair is, in excision repair the damaged DNA is removed, but in recombination repair, the damaged DNA is converted back to its original form without removing it. In excision repair, damaged DNA is recognized and cut out, and the resulting hole is patched by DNA polymerase l, using the DNA strand opposite the gap as the template. On the other hand, Recombinational DNA repair is a very complicated process that requires two DNA duplexes, and the exchange of a strand of DNA from one DNA duplex to the other .
2) Option 4 is the correct answer.
On exposure of a wild-type yeast to increasing doses of UV radiation, DNA repair mechanisms start to kick in which leads to a 6- to 8-fold increase in dNTP levels. The increase in dNTP pools dramatically improves survival following DNA damage, but at the same time leads to higher mutation rates. If the dimers are repaired before the DNA tries to replicate them, they have no effect on the cell. In all organisms mutations often occur during less accurate repair processes, accounting for the mutagenic action of UV radiation.
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