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Which of the following amino acids is incompatible with a-helix structures, but

ID: 19160 • Letter: W

Question

Which of the following amino acids is incompatible with a-helix structures, but compatible in ß-sheets?
a. Trp
b. Ala
c. Pro
d. Thr

I'm guessing it's (c) - Pro, since it's incompatible w/ alpha-helix and, in beta-sheet, it can do reverse turns. But what about (a) - Trp? It is incompat. w/ a-helix, but I wasn't able to find out whether bulky AA's are comp. or incomp. w/ beta-sheets...


Which of the following amino acids are most likely to be found in the interior of a globular protein?
a. glutamic acid and arginine
b. valine and isoleucine
c. proline and glycine
d. lysine and histidine

Interior of a globular protein would most likely have hydrophobic AA's, but both answers (b) & (c) are hydrophobic!; also, myoglobin/hemoglobin have histidine in the center (d)...

Explanation / Answer

Which of the following amino acids is incompatible with a-helix structures, but compatible in ß-sheets?
a. Trp
b. Ala
c. Pro correct
d. Thr

I'm guessing it's (c) - Pro, since it's incompatible w/ alpha-helix and, in beta-sheet, it can do reverse turns. But what about (a) - Trp? It is incompat. w/ a-helix, but I wasn't able to find out whether bulky AA's are comp. or incomp. w/ beta-sheets...


Which of the following amino acids are most likely to be found in the interior of a globular protein?
a. glutamic acid and arginine
b. valine and isoleucine
c. proline and glycine
d. lysine and histidine

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