The graph below depicts the effects of ethanol on receptor-mediated endocytosis

Question

The graph below depicts the effects of ethanol on receptor-mediated endocytosis of a glycoprotein in rat cells. Which of the following conclusions can be drawn based on the data provided? wered t of 1600 1400 1200 1000 800 600 400 200 -Chow Control -Ethanol 0 30 60 90 105 120 135 150 2500 r 2000 -Chow 1500 1000 500 Control -Ethanol 0 30 60 90 105 120 135 150 Time (min) Select one: xa. Ethanol inhibits receptor-mediated endocytosis by blocking clathrin association with the transmembrane receptor cross out O b. The effects of ethanol on receptor-mediated endocytosis increase with increasing ethanol concentration c. Ethanol causes cell death and therefore reduced receptor-mediated endocytosis cross out cross out nol may or may not directly affect receptor-mediated endocytosis but could affect global cell function cross out chow fed to the rats contains traces of ethanol that is provided to the rats as a positive control cross out

Explanation / Answer

Ethanol may or may not directly affect receptor mediated endocytosis but could affect global call function.

The graph just indicating that the amount of substrate provided to the cells for endocytosis is going down significantly when treated with ethanol. It does not throw light on the mechanism or caused of it. Also it is not repeated with varying concentrations of ethanol to comment I upon the trend of inhibition.

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