Hematology Case Study Module 6 A 52-year-old farmer complains of fatigue and cas

Question

Hematology Case Study Module 6 A 52-year-old farmer complains of fatigue and case of bruising Manual differential counts: WBC: 2.1 x 10L RBC: 2.61 x10/L Hgb: 7.9 g/dL Hct: 24.1% MCV: 92.3 MCH: 30.3 pg MCHC: 32.7 g/dL RDW: 12.9 gL PLT: 54.3 x10/L 1. What is the significance of the cell counts, indices, and peripheral blood smear image shown? A relative reticulocyte count and bone marrow analysis are represented as follows: Reticulocyte count: 0.3% Bone manrow biopsy image 2. Based on all the data provided, what condition is most likely? 3. What information is most diagnostic? 1 of 1

Explanation / Answer

1.) The process of cell counts, indices and peripheral blood smear has very important role in our lives. Cell counting is the determination of number of cells within a given volume of sample. It is a very useful process in medical diagnosis and treatment, and biological research that is used by scientists and medical practitioner all over the world. The concentration of these cells can provide critical information on the health status of the patients, if their concentrations are normal, too high or too low. Thus, cell counting aids in discovering a problem in its early phase.

Cell counting is also used in measuring cell viability. This is the calculation of the number of dead and living cells in a culture medium. It is useful in determining the life expectancy of a cancerous cell.

2.) It is given that after reticulocyte count and bone marrow biopsy, the observed reticulocyte count is 0.3%.

A normal result for an adult who are not anemic is around 0. 5% - 1.5%.

If the reticulocyte count is found to be higher that the normal percentage, it is a case of acute or chronic bleeding. InIthis the body compensates for the loss of RBCs by increasing the rate of RBCs production and by releasing RBCs sooner into blood, before they become more mature and thus the number of reticulocytes increases in blood.

If the reticulocyte count is lower than the normal percentage, it is a sign that the bone marrow is not working properly. This can redult from a bone marrow disorder such as aplastic anemia. Diminished production can also be due to some other factors like liver cirrhosis, kidney disease, chemotherapy radiation, a low level of erythropoeitin, lack of some nutrients such as vitamin B12, iron etc.

So, based on all the data given, it is most likely to have aplastic anemia or bone marrow failure.

3.) From the given information, it is clearly seen that the blood cell count is very low as compared to the normal range, which should be:

WBC - 3.5 - 10.5 x 109 /L

RBC - 4.32 - 5.72 x 1012 /L

Platelet - 150 - 450 x109/L

So, these are the most diagnostic information.

Related Questions

Navigate

• Browse (All)
• Browse H
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.