B. A complete blood smear and subsequent testing reveal that he has been infecte
ID: 193499 • Letter: B
Question
B. A complete blood smear and subsequent testing reveal that he has been infecterd by the parasite P. falciparum? a) What type of infectious agent is this? b) Describe its life cycle c) What is the mode of transmission? d) Douglas' is advised to begin treatment right away in order to prevent further complications, some of which can be life threatening. Explain what complications that the PA is worried about. What medications are used to treat patients such as Douglas who are already infected by P falciparum? e) E. The triage and phlebotomy staff at the Blood Center of Wisconsin would be interested to learn that Douglas has just returned from an area of the world with high rates of this disease when he next goes to give blood. Is it because he might spread this disease to them or others, or are there other reasons? If the former, explain how this works. References:Explanation / Answer
a) p. falciparum is a protozoa and is parasite in nature. They reside inside blood. It is responsible for malaria fever in human beings.
b) P. falciparum contain two host in its life cycle- human host and Anopheles mosquito. when a mosquito bites a human, the sporozoites stage of the parasite passed towards the human. Inside the human body, the sporozpoits then infect liver and convert to schizonts stage , which contains mutiple nucli. Next schizonts get metured inside the liver and release merozoits into the blood stream. Merozoits are able to bind with the erythrocyte. Inside the red blood cell, merozoits produces trophozoite and then schizont stage. Next schizont stage matures to produce more merozoit which rupture the red blood cell and infect another red blood cell.
On the other hand a meroizoit also transforms into gametocyte like male and female gametocytes. Now, when a mosquito bites a infected person these gamotyctes will enter the midgut of mosquito . Inside the midgut they will produce zygotes and ultimately develop ookinetes. When ookinates penetrate the midgut wall, and transform to oocysts. These oocysts once again release sporozoits which can go towards the salivary gland and can next another human when the mosquito bites another person.
C) these parasite is get transmitted by Anopheles mosquitoes.
d) If remain untreated, severe malaria can produce organ failure, difficulties or shortness in breathing, seizures, severe degree of anemia. In some cases, death can happened.
e) Generally drugs such as chloroquine, doxycycline, mefloquine or quinine are administrated to the pateint,
f) In malaria the parasites are situated inside the erythrocyte, it is possible that the disease can spread by blood transfusion. It can also spread by use of shared syringe which has been already used by contaminated person.
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