Use the resources below to answer question 1. This question requires more than j

Question

Use the resources below to answer question 1. This question requires more than just reading the primary paper.

The PubMed Id for the main paper is PMID: 23667324

1. (2 pts.) Using Fst (fixation index) as a measure, rank the following pairs from most similar to least similar (this question draws on multiple papers).

A. Cornwall (England) / Devon (England)

B. Seri (Mexico) / Lacandon (Mexico)

C. Tojolabal (Mexico) / Mayan (Mexico)

D. Scottish / Welsh

E. Europeans / Chinese Your answer can be an order of letters (e.g. ABCDE, which would imply you thought A had the lowest FST and E had the highest FST).

Readings: Primary paper: Ralph and Coop 2013 PLoS Biology 11(5):e1001555 "The geography of recent genetic ancestry across Europe." Background: Gibson. "A Primer of Human Genetics." Chapter 3. Human Evolution Chapter 4. Normal Variation Graham Coop's blog: gcbias.org Fan, Hansen, Lo and Tishkoff 2016. Science 354: 54. "Going global by adapting local: A review of recent human adaptation" PMID 27846491 Nielson, Akey, Jakobsson, Pritchard, Tishkoff and Willerslev 2017 Nature 541: 302. " Tracing the peopling of the world through genomics" PMID 28102248 Accessory readings (genetic structure of specific groups): Leslie et al. 2015. Nature 519: 309. "The fine-scale genetic structure of the British population." PMID 25788095 Moreno-Estrada et al. 2014 Science 344: 1280. "Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits." PMID 24926019 A comment on race: Chakravarti 2015 Cold Spring Harbor Perspectives in Biology 7:a023358. "Perspectives on Human Variation through the Lens of Diversity and Race." PMID 26351717

Explanation / Answer

E. European and chinese

D. Scottish and welsh,

A. Cornwall and Devon

B. Seri and lacandon

C. Tojolabal and mayan

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