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Table 1. The Genetic Code First position Second position Last position UUu PheUc

ID: 195420 • Letter: T

Question

Table 1. The Genetic Code First position Second position Last position UUu PheUcU Ser UAU Tyr UGU Cys UUC Phe UCC Se UAC Tyr UGC Cys UUA Leu UCA Ser UAA STOP UGA STOP UUG Leu UCG Ser UAG STOP UGG Trp CUU Leu CCU Pro CAU His CGU Arg CUC Leu CCC Pro CAC His CGC Arg CUA Leu CCA Pro CAA Gln CGA Arg CUG Lu CCG Pro CAG Gln CGG AUU lle ACU ThrAAU Asn AGU Ser AUC lle ACC Thr AAC Asn AGC Ser AUA lle ACA Thr AAA Lys AGA Arg AUG met ACG Thr AAG ys AGG Arg GUU Val GCU Ala GAU Asp GGU Gly GUC Val GCC Ala GAC Asp GGC Gly GUA Val GCA Ala GAA GluGGA Gly GUG Val GCG Ala GAG Glu GGG GlyG I. a. (4pts) List two structural features of a mRNA 5'cap. b. (4 pts) The 5 cap has two roles, identify these by filling the appropriate bubble. O It enhances the recognition of the transcript by the translation machinery O It associates with activators to increase transcription rates O It phosphorylates serine residues in the CTD of RNA Pol II O It protects the transcript from nuclease hydrolysis O It increases how frequently RNA Pol II is recruited to the initiation site

Explanation / Answer

Answer (a) The two structural role in 5' cap of an m-RNA are as follows:

1. 5' cap region protects the m-RNA from the degrading action of exonucleases because of the formation of unusual 5'-5' linkage.

2. 5' cap is also important for the binding of the ribosomes in the translation process.

Answer (b) The correct answer is 3rd option "It protects the transcript from nuclease hydrolysis".

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