Describe the procedure of the “provocative test” and adverse reaction of the pat

Question

Describe the procedure of the “provocative test” and adverse reaction of the patient in response to the test.

Provocative Tests

At the age of seven the patient fasted for 22 hours. Blood was collected every two to four hours from hour 14 to hour 22 for measurements of blood glucose and plasma free fatty acid and b-hydroxybutyrate concentrations. Urine was collected for organ- ic-acid analysis at the end of the fast. After a 15-hour fast, the boy was given 1.5 g of medium-chain triglycerides per kilogram of body weight orally, and then plasma b-hydroxybutyrate was measured at hourly intervals for 3 hours, blood glucose was meas- ured every 15 to 30 minutes for 3 hours, and urine and plasma were collected for organic-acid analysis at 3 hours. A similar pro- tocol was followed after the child had fasted for 12 hours and was then given long-chain triglycerides in the form of safflower oil (1.5 g per kilogram). The boy’s parents gave informed consent for all the diagnostic investigations.

Explanation / Answer

Provocative test in medical is when a person is exposed to a thing that will claim to produce a reaction for the thing. Du ring these fasting only water is allowed

Adverse reactions of patient during procative tests can be # several skin allergy

# reaction to the doses

# negative results of the test

# bias results if patient Don't do fasting properly

# chances of patient having lower blood sugar & having much ketone bodies in urine

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