1) (2pts) This is a picture of dUTP-a nucleotide which according to our rules ma
ID: 197790 • Letter: 1
Question
1) (2pts) This is a picture of dUTP-a nucleotide which according to our rules makes no sense. It has a "U" base and a DNA sugar. In fact, this nucleotide is produced as a precursor to dTTP, which is then used to make DNA the image circle the part of this molecule that is the nitrogenous base "U NH image add the atom (s) on to the sugar that are necessar to convert this back into the RNA nucleotide. HO-P-O-P-O-P-O C) Label the 5' and 3' end of this molecule 2) (1 pts) The molecule dTTP is required ONLY for DNA synthesis, and inhibitors for the enzymes that produce dTTP have been used as anti-cancer agents. When do cells make new DNA, and why would preventing DNA therapy? need to production be a good idea for a cancerExplanation / Answer
2. Ans-
DNA synthesize needs to make new cells when existing cells divide to produce new cells. If DNA synthesize doesn’t take place, the size of the cell would die. Therefore, it is important that DNA synthesize doubles the cells splitting during mitosis and meiosis. Each cell requires a proper instruction for their functions. So the DNA needs to be copied before cell division to receive instructions.
Cancer therapy includes surgery, chemotherapy, and radiotherapy. Chemotherapy mainly targets the rapidly dividing cells and prevent the cancer cells for further dividing. For example, DNA damaging agents such as cisplatin block replicative polymerases, 5-fluorouracil, and hydroxyurea produce toxic metabolites that incorporate into DNA to reduce nucleotide pools, and topoisomerase inhibitors like camptothecin and etoposide inhibit DNA synthesis.Radiation therapy kills cancer cells by damaging their DNA.Radiation therapy includes damage DNA directly, single-stranded breaks and double-stranded breaks in the cells. Therefore, prevention of DNA synthesize would be a good idea for cancer therapy.
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