conditions? Why? Endorphins are natural peptide hormones in our body that regula
ID: 197952 • Letter: C
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conditions? Why? Endorphins are natural peptide hormones in our body that regulate a umber of neurochemical processes. Perhaps most amously, they act as neurotransmitters that bind the opioid receptors in our brains (the same receptors bound by morphine and heroin), stimulating feelings of well-being HO and providing pain relief. NH2 H OH One of the most common endorphins is Leu-Enkephalin, shown above. 7. What is the amino acid sequence of Leu-Enkephalin? Estimate its pl. 8. Leu-enkephalin relies on a membrane-bound protein receptor, called an opioid receptor, to interact with nerve cells. What amino acids might you expect to find located in the active binding site of the opioid receptor for Leu-Enkephalin? Why?Explanation / Answer
7. The amino acid sequence of Leu-Enkephalin is Tyr-gly-gly-phe-leu.
8. Opioid are the substance has opioid receptors,they are used in making of anesthetic and pain reliver drug.
In leu-enkephalin the opioid receptors are Recently the structures of the three , , and opioid receptors were solved by crystallography. They will intracted with nerve cell and recieve signal. It is bind up with different type of protein it may be folded or unfolded type of protein which are binding on activation site according to orgnism and type there is many sub division of opioid receptor are present and attachted with different protein.
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