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What is wrong with the way the nucleotides are joined? A. The 5\' carbon of the

ID: 200616 • Letter: W

Question

What is wrong with the way the nucleotides are joined?

A. The 5' carbon of the top nucleotide is connected to the 2' carbon position of the sugar in the bottom nucleotide, but a phosphate attached to the 5' carbon of the bottom sugar should be covalently linked to the 3' OH group of the top sugar.

B. The 5' carbon of the bottom nucleotide is connected to the 2' carbon position of the sugar in the top nucleotide, but a phosphate attached to the 5' carbon of the top sugar should be covalently linked to the 3' OH group of the bottom sugar.

C. The 5' carbon of the bottom nucleotide is connected to the 2' carbon position of the sugar in the top nucleotide, but a phosphate attached to the 5' carbon of the bottom sugar should be covalently linked to the 3' OH group of the top sugar.

D. The 5' carbon of the top nucleotide is connected to the 2' carbon position of the sugar in the bottom nucleotide, but a phosphate attached to the 5' carbon of the top sugar should be covalently linked to the 3' OH group of the bottom sugar.

Base OH CHC H OH H O OH-CHC H OH H O

Explanation / Answer

Ans. C.The 5' carbon of the bottom nucleotide is connected to the 2' carbon position of the sugar in the top nucleotide, but the phosphate attached to the 5' carbon of the bottom sugar should be covalently attached linked to the 3'OH group of the top sugar.

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