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7. For each of the statements below (a-d) circle the correct choice, TRUE or FAL

ID: 200868 • Letter: 7

Question

7. For each of the statements below (a-d) circle the correct choice, TRUE or FALSE. If the statement is FALSE, correct the statement with new information in the space provided. Do not simply negate the statement (10 pts). a) TRUE or FALSE: In Leukocyte Emigration, leukocytes arrest on the endothelium via P-and E- selectin binding to sialyl Lewis b) TRUE or FALSE: In the Leukocyte Emigration process, the leukocytes express chemokines that bind to chemokine receptors present on the endothelium. c) TRUE or FALSE: Leukocyte Emigration is the process by which T and B cells migrate into lymph nodes d) TRUE or FALSE: NADPH oxidase is the enzyme that catalyzes the production of reactive nitrogen species in T cells e) TRUE or FALSE: Type I interferons are tissue-damaging toxins produced by viruses

Explanation / Answer

b. False: Chemokines are expressed by macrophages which then help mediate leukocyte emigration.

c. False: It is a process in which leukocytes travels through the endothelial gap junctions of blood vessels in times of inflammation.

d. False: Nitric oxide catalyses the production of reactive nitrogen species in T cells.

e. False: Type I interferon regulate the activity of the immune system, and are not produced by viruses.

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