8. Indicate whether each of the following statements is true of clathtin, COPI,

Question

8. Indicate whether each of the following statements is true of clathtin, COPI, or COPlI coated vesicles. Each statement may be true for one, several, or none of the 3 types of coated vesicles. Write the name(s) of the coated vesicles next to letter of the appropriate statement(s). (1 pt each) a. Has a role in forward directional transport from the ER to the Golgi complex b. Has a role in transport of acid hydrolases to late endosomes c. Has a role in retrograde traffic through the Golgi complex back to the ER d. The formation of the coat is regulated by small GTP binding proteins e. Fusion of the vesicle (after uncoating) is dependent on the action of Rab proteins and SNARE pairs f. Binding of the coat protein to the LDL receptor is mediated by an adaptor protein T

Explanation / Answer

COP-coated vesicles participated in movement of vesicles in the forward direction from ER to Golgi and within Golgi, but vesicles coated with clathrin transport proteins from the Golgi to the surface of the or from the cell surface to endosomes. Adaptor protein is one more essential component of the clathrin coated vesicles in addition to clathrin. Binding of LDL receptor to clathrin coated protein facilitate by an adaptor protein complex.

A coatomer, COPI is a protein complex, which coats vesicles that carrying proteins from the Golgi cis end back to the place where they were produced initially i.e. endoplasmic reticulum, and between Golgi compartments. Whereas, coatomer COPII, is a type of coat protein vesicle which carry proteins from the endoplasmic reticulum to the Golgi apparatus, process is called as anterograde transport. For the fusion of COPII vesicles to acceptor membrane, Rab GTPase and SNARE proteins are essential.

a - COP II, b- clathrin, c- COPI, d- COP I and COP II, e- COP II f- clathrin

Related Questions

Navigate

• Browse (All)
• Browse 8
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.