8. In which of the following solvents would you expect Ibuprophen (structure sho

Question

8. In which of the following solvents would you expect Ibuprophen (structure shown below) to be soluble? OH a. H2O b. 1M HCI c. 1M NaOH d. None of the above 9. Which of the following would increase the retention time for a pure compound during analysis by gas chromatography? a. Decreasing the flow rate of the inert gas b. Increasing the temperature of the column. c. Injecting twice as much sample d. a and c 10. Hexane has a refractive index of 1.3749. If the hexane is contaminated with an unknown liquid, how will this affect the refractive index? a. The refractive index will not change. b. The refractive index will be higher than 1.3749. c. The refractive index will be lower than 1.3749. d. None of these predictions can be made about the refractive index.

Explanation / Answer

8. Option C: 1 M NaOH. Because of weak acid carboxylic acid, ibuprofen can react with NaOH to form Sodium salt of ibuprofen.

9. Option A: decreasing flow rate of inert gas, will increase retention time for a pure compound.

10. Option D: None of these prediction can be made about the refractive index because of density is unknown of unknown liquid, and refractive index is proportional to density, it can not be predicted.

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