You\'re working at the medical examiner\'s office at San Francisco County Hospit

Question

You're working at the medical examiner's office at San Francisco County Hospital. It has been a particularly light day, with only 1 homicide and a dead chipmunk that you checked over for rabies. The chipmunk didn't have rabies, and you're ready to go home. Just as you're flipping the switch, you get a call from your secretary. "Francesca," he says. "We've got a dead kid up here that you'll want to look at right away. Might be foul play Thinking of your four-year old daughter waiting for you at home, you grimace. "OK Jon, I'm heading to the morgue." Performing autopsies on kids is the least favorite part of your job. But you are paid to solve medical mysteries, and it looks like you've got one here. In the morgue, you find the report from the hospital. Glancing over it, you notice a narrative of the girl's last hours and read it carefully: At 10 AM, mother returns from the store to find girl vomiting, not feeling well, and sleepy. Mother put girl to bed. Ten minutes later, she noticed that the child's breathing became irregular and slow. She tried to wake her daughter but was not able to do so. The child became comatose. At noon, the girl was admitted to the hospital, with no heartbeat or spontaneous breathing. A police report states the following: The parents discovered that the girl had been giving her dog a bath using a flea dip called Fleacide. According to the label on the container, Eleacide is an insecticide made of plant material only and appropriate for external use on animals. It contain rotenone, which is known to be toxic in high levels. PART 1:The Flea Dip 1. What could have been in the flea dip that killed the girl? How could a product that is normally harmless to humans and pets have killed the girl? PART 2: Autopsy Report The girl died within two hours of first vomiting, immediate cause of death was hypoxia (lack of oxy gen) Tissue sections from the kidneys, lungs, thymus, and heart show massive cell death; Staining with cellular dyes indicates that the mitochondria within the affected tissues were damaged 2. Given the autopsy report, and recalling your knowledge from your reading about the functions of cellular organelles, what functions of the cell did the Fleacide affect?

Explanation / Answer

PART 1

Rotenone present in flea Dip killed the girl. Rotenone is moderately lethal to humans in water rotenone last for very long time and for a child lowest lethal dose is 143 mg/kg soo continues dose of rotenone can be lethal

part 2

Fleacide effect the Cellular Respiration pathway

In which glucose is breakdown with the help of mitochondria in the presence of oxygen and without oxygen mitochondria stop functioning and energy production stop

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