17. Based on the following replication bubble, which of these statements is true

Question

17. Based on the following replication bubble, which of these statements is true? 3' A) X and Y are leading strands, W and Z are lagging strands B) X and Z are leading strands, W and Y are lagging strands C) X and W are leading strands, Y and Z are lagging strands D) W and Z are leading strands, X and Y are lagging strands E) W and Y are leading strands, X and Z are lagging strands 18. A mutant E coli strain defective in just the 3'-to-5' exonuclease activity of DNA polymeraselll would likely show the following characteristics (circle all that apply)- A) DNA interrupted by regions of RNA B) DNA lacking supercoiling C) DNA containing breakage due to torsional stress D) DNA containing more mis-match mutations than normal 19. What fraction of the nucleotides in a double-stranded DNA molecule are cytosine and thymine (% C and 96 T added together)? A)25% B) 50 % c) 75 % D) 10096 E) It depends on the DNA sequence 20. The term mutation refers to A) only changes in the genome that result in new phenotypes B) only changes in the genome that result in new proteins. C) only changes in the genome that result in loss of function. D) a heritable change in the genome of a cell. E) any change in the cell that changes its survival chances. 21. In humans, there are over 40 genes encoding various helicase enzymes inactivation of just one of the many genes coding for helicases may lead to (circle all that apply) A) lactose intolerance B) amyotrophic lateral sclerosis C) Floating-Harbor Syndrome D) one form of autism E) Down Syndrome

Explanation / Answer

17-A(REPLICATED IN 3'-5' DIRECTION)

18--D

19--b(C BINDS WITH G,A WITH T SO THERE IS 50% OF C&T)

20--D

21--E

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