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6. What must a newly made protein have in order to get into the inside (lumen) o

ID: 203671 • Letter: 6

Question

6. What must a newly made protein have in order to get into the inside (lumen) of the rough endoplasmic reticulum? 7. What is it called when a protein receives a sugar tag? 8. How do proteins move between the rough endoplasmic reticulum and the golgi apparatus? 9. What do proteins receive when they move through the stacks (cisternae) of the golg apparatus that helps them get sorted into the correct transport vesicles? 10. What is the definition of enthalpy? 11. What is the definition of entropy?

Explanation / Answer

Ans.6 The newly made protein must have signal sequences which are long sequences of about 20 amino acid residues that contains a hydrophobic membrane crossing domain at the N terminal end.

This signal peptide is recognized by the signal recognition particle in the ER membrane and this allows the ribosomes to attach to the ER by means of special SRP receptor in the ER membrane. As ribosomes attached this will form a translation channel and protein inserted into ER linen.