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18. These results confirm that fat is indeed being deposited in Jessie’s liver,

ID: 203860 • Letter: 1

Question

18. These results confirm that fat is indeed being deposited in Jessie’s liver, a health hazard that Jessie was completely unaware of! Jessie’s liver fat concentration supports the hypothesis that fatty acid oxidation is impaired. Jessie is very grateful for your help so far. In a previous investigation you also found evidence that the specific problem is likely to be the inability to transport long-chain fatty acids into the mitochondria, since short- chain acids are processed normally. The exact problem and cause still remain to be determined, so you must continue with your investigations. Consider this question before returning to additional investigations: Which of the following proteins are involved in the transport of long-chain fatty acids into the mitochondria? (Select ALL that apply!) A. Pyruvate dehydrogenase B. Carnitine acyltransferase I (CAT I) C. Citrate synthase D. Carnitine acyltransferase II (CAT II) E. Aldolase F. Acyl-CoA dehydrogenase

Explanation / Answer

CAT I, CAT II, acyly-CoA dehydregenase, pyruvate dehydrogenase are the proteins involved in transportation of long chain fatty acid into mitochondria

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