Glycolysis and gluconeogenesis are concurrent and complementary metabolic pathwa

Question

Glycolysis and gluconeogenesis are concurrent and complementary metabolic pathways. Which of the following IS NOT TRUE a) glycolysis and gluconeogenesis regulate the availability of glucose in the cell b) all enzymes and intermediates used in glycolysis and gluconeogenesis are the same, glucose, respectively anabolizes acetyl-CoA and pyruvate to glucose. fructose 16P into fructose 6P (final step) in gluconeogenesis uses pathway specific ) glycolysis catabolizes glucose to pyruvate and acetyl-CoA and gluconeogenesis d) the conversion of pyruvate into phosphoenolpyruvate (first step) and conversion of enzymes which are not shared with glycolysis

Explanation / Answer

Option b is correct answer

All enzymes used in glycolysis and gluconeogenesis are not same. In glycolysis, conversion of fructose-6-phosphate to frutose-1,6-bisphosphate requires the enzyme phosphofructokinase while in gluconeogenesis, conversion of fructose-1,6-bisphosphate to fructose-6-phosphate requires enzyme fructose-1,6-bisphosphatase

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