QUESTION 4 What causes synaptic facilitation? Activation of synaptotagmin by mea

Question

QUESTION 4 What causes synaptic facilitation? Activation of synaptotagmin by means of phosphorylation Release of synaptic vesicles loaded with extra neurotransmitter Release of greater than usual number of synaptic vesicles Buildup of Ca2+ in the presynaptic terminal QUESTION 5 What mechanism is necessary for growth cone motility? Polymerization and depolymerization of actin and tubulin Exposure to semaphorins Nuclear localization of integrins Presence of netrins QUESTION 6 Which condition(s) must be met to induce LTP? Glutamate must be released from the presynaptic terminal Glutamate must open the postsynaptic AMPA receptors The postsynaptic membrane must be depolarized for a period of time Mg2+ block must be expelled from NMDA receptors to allow Ca2+ influx All of the above

Explanation / Answer

Q. 4. Answer is D as:

Ca2+ plays a significant role in transmitting signals at chemical synapses.  A higher concentration of Ca2+ enables synaptic vesicles to fuse to the presynaptic membrane and release their contents into the synaptic cleft to ultimately contact receptors in the postsynaptic membrane. Hence, short-term facilitation results from a build up of Ca2+ within the presynaptic terminal.

Q.5 Answer is A

Actin and tubulin are present in growth cones. As The dynamics of actin filament polymerization, depolymerization and linkage to other components of the P-domain are responsible for major aspects of growth cone motility.

Q. 6. Answer is All of the above as:

Long-term potentiation (LTP) is induced by the all these affecting factors.

Related Questions

Navigate

• Browse (All)
• Browse Q
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.