(40 111 1 2:08 AM 1. What is biomaterials? Why do we study biomaterials? What is
ID: 204593 • Letter: #
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(40 111 1 2:08 AM 1. What is biomaterials? Why do we study biomaterials? What is the 4 typical types of biomaterials? Current stents used in clinics usually fall short on clinical needs due to thrombosis (blood clotting) and restenosis (re-narrow of the blood vessel). How to create a new design to enhance the performance of a stent? (describe from material types, mechanical integrity/properties, biocompatibility, corrosion, and other practical perspectives) 2. 3. Can you design a new medical suture from the material perspectives? And justify your design. 4. Can you list 3 ways to induce the crosslinking/self-assembling of polymers like hydrogels? 5. Proteins can be adsorbed on the surface of biomaterials. What is the difference between physical adsorption vs chemical adsorption?Explanation / Answer
1 ans: Biomaterial is any substance that has been engineered to interect with biological systems for a medical purpose or a diagnosticone.
Example:- used to repair a tissue function of body
There are 3 main types of biomaterials.1) Bioinert 2) Bioresorbable 3) Bioactive
2 ans: we can enhance stent effectiveness with nanofeatures by using drug eluting stents. In this technique drugs locally that suppress vascular smooth muscle cell prolifration.
3 ans: for making suture we can use sheep submucosa origin from nature.
Construction : monofilament
Coatung material : chromium salt
Colour : brown
Size: 3-5 mm
Strength retention : 21-28 days
Absobtion time : 90 days
Absobtion profile : proteolytic enzymatic digestion.
4 ans : 3 Ways to induce the crosslinking of polymers like hydrogels are as follows
(1) by stereocomplex formation
(2) crosslinking by ionic interaction
(3) crosslinking by protein interaction .
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