Are a group of transmembrane protein receptors that cross the phospholipid bilay

Question

Are a group of transmembrane protein receptors that cross the phospholipid bilayer seven times. They bind with a ligand outside the cell and activate signal transduction pathways inside the cell and, ultimately cellular responses. Choose ] G protein complex is attached to the ligand gated receptor and consists of 3 subunits designated alpha, beta, and [ Choose ] Term of the signal molecule that binds to the GPCR and causes a conformational (shape) change in the receptor and activates it. [ Choose ] True or False: A G protein subunit can activate a membrane protein/enzyme known as adenylate cyclase, which will catalyze the formation of many intracellular cAMP (cyclic adenosine monophosphate) molecules that will continue to carry the signal and act as second messengers. IChoose l True or False: One of the actions of CAMP is to bind to and activate an enzyme called protein kinase A. Protein kinase A phosphorylates (addition of phosphate groups) of other enzymes or target proteins. Choose ] Com... JPG

Explanation / Answer

Membrane receptors

Gamma receptors

Ligand

True, One common target of activated G proteins is adenylyl cyclase, a membrane-associated enzyme that, when it is activated by the GTP-bound alpha subunit, it catalyses synthesis of the second messenger cAMP from molecules of ATP.

True, major effect of cAMP is to bind to and activate protein kinase A

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