Problems 9-10. In 1984, Martinez-Castro et al. (Cytogenetics and Cell Genetics 3

Question

Problems 9-10. In 1984, Martinez-Castro et al. (Cytogenetics and Cell Genetics 38:310-312) published a pedigree of a fam homozygous for t(13q, 14q), two who were heterozygous for t(13q;14q), and one with a normal karyotype. 9. Should there be a lost fertility in the three homozygous t (13q:14q) offspring? A. Yes B. No 10. Calculate the probability of this particular outcome for this family (three translocation homozygotes, two translocation heterozygotes, and one normal karyotype). Assume that unbalanced gametes are viable. C. 0.029 A. 0 B. 0.125 D. 0.500 E. 0.660 F. 0.059 G. 0.008 H. 1

Explanation / Answer

1-yes there should be a lost fertility in the three homozygous offsp.

2- (h) 1..

Hope u understand the answer

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