The Hardy-Weinberg equation can be used to calculate the genetic variation of a
ID: 208010 • Letter: T
Question
The Hardy-Weinberg equation can be used to calculate the genetic variation of a population in equilibrium (i.e., it is not evolving). Basically, Hardy-Weinberg equilibrium states that the amount of genetic variation is constant from one generation to the next – that is, the frequency of alleles remains the same over time.
The Hardy-Weinberg equation is very simple: p2 + 2pq + q2 = 1
Imagine we are following a single gene with two alleles, A and a. Based on the Hardy-Weinberg equation,
a) What is the frequency of the following genotypes:
AA: _____ Aa: _____ aa: _____
b) What is the frequency of each allele:
A: _____ a: _____
Explanation / Answer
According to Hardy Weinberg law if the equation is- p2 + 2pq + q2 then
The frequency of genotypes would be:
AA- p2
Aa - pq
And -aa - q2
And the frequency of each gene can be calculated by
A - p and a -q.
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