Multiple Choice-Circle the correct answer(s). 1) Which lines of evidence do not

Question

Multiple Choice-Circle the correct answer(s). 1) Which lines of evidence do not help explain the phenomenon of synaptic facilitation? a. Ca2+ concentrations typically increase faster than they decrease in presynaptic b. neurons c. at low levels of neural activity, not all synaptogamin molecules are bound by Ca2+ d. sustained neural activity for 250ms results in declining postsynaptic membrane potentials from 100-250ms 2) In a glutaminergic synapse, the presynapse is being tetanized at levels that cause LTP in positive control animals, while the postsynapse is also depolarized. Simultaneously, a drug that blocks AMPA receptors is applied. What would be the effect? a. AMPA receptor numbers would not increase in the postsynapse b. LTP would occur, showing EPSPs identical to positive control animals c. AMPA receptor numbers would increase in the postsynapse, but EPSPs would not be elevated as in positive controls. d. AMPA receptor numbers would increase in the postsynapse, but once the AMPA blocking drug were washed away EPSPs would return to levels seen in negative (non- tetanized) control animals

Explanation / Answer

Q1.

Ans:- a) Ca2+ concentration typically increses from sarcoplasmic reticulum is helpfull.

b) Neurons is also helpfull

d) sustained neural activity is also required

But C) at low levels of neural activity not all synaptogamin molecules are bound by Ca2+ is not helpfull.

Q.2.)

Ans.B. LTP would occure,showing EPSPs identical to positive control animals.

Explanation:- one of the most widely and thorouly investigated forms of plasticity in nervous system is long term potentiation. i.e. LAP

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