Multiple Choice-Circle the correct answer(s). 1) Which lines of evidence do not

Question

Multiple Choice-Circle the correct answer(s). 1) Which lines of evidence do not help explain the phenomenon of synaptic facilitation? Ca2+ concentrations typically increase faster than they decrease in presynaptic neurons at low levels of neural activity, not all synaptogamin molecules are bound by Ca2+ sustained neural activity for 250ms results in declining postsynaptic membrane potentials from 100-250ms a. b. d. 2) In a glutaminergic synapse, the presynapse is being tetanized at levels that cause LTP in positive control animals, while the postsynapse is also depolarized. Simultaneously, a drug that blocks AMPA receptors is applied. What would be the effect? a. AMPA receptor numbers would not increase in the postsynapse LTP would occur, showing EPSPs identical to positive control animals c. AMPA receptor numbers would increase in the postsynapse, but EPSPs would not be elevated as in positive controls. AMPA receptor numbers would increase in the postsynapse, but once the AMPA blocking drug were washed away EPSPs would return to levels seen in negative (non- tetanized) control animals d.

Explanation / Answer

1) is correct synaptic facilitation does not involve this evidence where low level s of neural activity is dealt with.calcil calcium increase s typically then decrease s in presynaptic neurons,ca leads to exocytosis of vesicles through involvement of several protein in vesicular membrane and release acetylcholine into synaptic cleft B-)and they decrease later

Neurons are present during synaptic facilitation

Sustained neural activity actual decline s podt synaptic membrane potential

2))as the nerve os tetanized at levels that cause ltp in positive ccontrol animal s while post synapse is depolarized conduction is not possible ampa is blocked whoch is supposed to maintain fast transmission so ltp would occur so correct

2))

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