PLease explain, thank you! Mustard gas is an alkylating agent, and can modify ba

Question

PLease explain, thank you!

Mustard gas is an alkylating agent, and can modify bases by adding alkyl groups to nitrogenous bases. Which of the following processes would most likely repair the damaged DNA caused by mustard gas exposure of World War I soldiers during the third battle of Ypres? 3. A) Ms. Scarlett in the library with the lead pipe. (By not choosing this answer, you aver that you are not totally Clueless) B Direct repair Base addition by thymine dimer repair D SOS repair E Nucleotide excision repair

Explanation / Answer

The answer for this question will be E that denotes the nucleotide excision repair, because the research study demonstrated that the nucleotide excision repair-competent cells are also capable of repairing reporter plasmid damaged by mustard gas and bringing luciferase expression from the plasmid to higher levels than in nucleotide excision repair-deficient cells using the dual luciferase host cell reactivation assay. Also, the yeast mutants deficient in nucleotide excision repair are proved to be much more sensitive to mustard gas than wild-type cells. This indicated that the nucleotide excision repair could repair the damaged DNA caused by the mustard gas exposure of World War I soldiers during the third battle of Ypres.

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