What Do I Remember? 1. Describe the contributions of each of these researchers i

Question

What Do I Remember? 1. Describe the contributions of each of these researchers in our understanding of DNA: Miescher; Griffith; Hershey and Chase; Avery, MacLeod, and McCarty; Levene; Franklin and Wilkins Why were the experiments of Watson and Crick so significant? important to the functions of DNA. ing protein (remember to look for the start codon) GUAGUAAACCG tion to produce a functional protein. were changed on half of the tRNA molecules? mutation in a gene? 2. 3. Describe what is meant by "base pairing" and why this is so 4. Translate the following mRNA sequence to its correspond- CACUAACGUAAUGCCACGUUUCGGCAACAUACG- 5. Describe each of the steps that must occur during transla- 6. What would be the consequence for the cell if the anticodons 7. Why are eukaryotic cells not immediately affected by a 8. Describe the functions of the lactose operon with and with out lactose present.

Explanation / Answer

1.

a) Friedrich Miescher was responsible in isolation of the protein nucleus, which is a protein that is associated with the DNA, isolated from the nuclei of the cell. He was the first scientist who was responsible in the identification of DNA as a seaparate molecule

B) the experiment conducted by Griffith was the first that suggested bacteria is able to transfer its genetic material and this process is referred to as transformation. He suggested the ability of bacteria in changing its form.

C) Hershey and chase were able to prove to the world that DNA is a hereditary material.

D) Avery, MacLeod and McCarty: he was one of the major contributors in immunochemistry. He was renowned for his experiment in which he isolated the genetic material DNA of which chromosomes as well as genes are composed of.

E) levene had most famously been known for the incorrect hypothesis that he formulated for tetra nucleotide DNA. He is most commonly known for the tetranucleotide hypothesis , wherehe proposed that DNA is composed of adenine, guanine, cytosine and thymine in equal amounts.

F) franklin and Wilkins: the work proposed by Rosalind Franklin supported the presence of the double helix. They discovered the double helix which formed the basis of the further structures of DNA. She gave the X Ray pictures of DNA which unlocked the details of the hereditary material.

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