4 Coupled reactions involving ATP Al iving things carry out mtabolsm, despite th

Question

4 Coupled reactions involving ATP Al iving things carry out mtabolsm, despite the fact that many metabokc reactions are enargeticaly unfaorable To drive an unfaworable endergonic reaction, a cel munt couple t with a favorabiexgoic maction. The folloning dagram vstrates this prindple In ths dagram, the reaction exergonk proteinarmina acds AOP ATP Higher Energy Lower Enorgy ADP course of reaction- For the overal coupled chemical reaction to occur sporcanecusly, the change in free esergy of the favorabie reaction rust be greater than the change ie free energy of the unfavorable reaction (labsoed O Type here to search

Explanation / Answer

1. The synthesis of a polypeptide from individual amino acids is unfavorable (endergonic). This step is represented by 3 in the diagram.

2. Endergonic reactions are driven by coupling them with ATP hydrolysis.

Amino acids + ATP -----> Protein + ADP + Pi

So, option C is correct.

3. ATP can drive endergonic reactions only if the dG of the reaction is less than -7.3 kcal/mol.

So, option B is correct.

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