This i what is a driving force that makes the following reaction go forward in g

Question

This i what is a driving force that makes the following reaction go forward in glycolysis (5 pts). 7. This is one of is one of reactions in glycolysis. ) Predict whether the reaction is likely to be reversible or irreversible ia 2- 8. During exercise, your muscle may convert pyruvate to lactate. However, this step does not produce any ATP.I explain why this conversion is important and necessary in muscle during exercise (5 pts). Make sure to explain in detail. 9. Acetyl-CoA carboxylase is one of enzymes involved in lipid biosynthesis that we will learm coenzyme necessary for this enzyme? ii) Briefly, explain the role of this coenzyme (6 pts). 10. Predict whether the following molecules would increase or decrease the rate of the given reaction or p (a) ATP for gluconeogenesis (b) Alanine for gluconeogenesis (c) Acetyl-CoA for glycolysis (d) Fructose 1,6-bisphosphate for pyruvate kinase (e) AMP for glycolysis 10. tion or pathway (5 pts).

Explanation / Answer

7.

i) The reaction is likely to be reversible as it is mediated by phosphoglycerate mutase, an isomerase.

ii) The driving force is the high concentration of 3 - phosphoglycerate than that of the 2 - phosphoglycerate.

8. The pyruvate to lactate conversion step does not produce any ATP but conversion of glucose to pyruvage produces 2 molecule of ATP. These ATP can meet the immidiate energy requirements of muscle contraction. So this this conversion is important and necessary in muscle during exercise.

9.

i) The coenzyme pantothenic acid is necessary for acetyl-CoA carboxylase.

ii) This Coenzyme is carboxylated by the enzyme to produce malonyl-CoA.

10.

ATP for gluconeogenesis Decrease Alanine for gluconeogenesis Decrease Acetyl-CoA for glycolysis Increase Fructose 1,6-bisphosphate for pyruvaye kinase Decrease AMP for glycolysis Increase

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