Case 1: As a child growing up on a dairy farm, Luke was responsible for helping

Question

Case 1: As a child growing up on a dairy farm, Luke was responsible for helping with the milking. At the age of seven, he developed a seeping lesion on his wrist. The lesion progressed to a red and encrust sore. When a physician was consulted, she was not concerned, and told the parents simply to watch the sore for secondary bacterial infection. 1. 2. What occurs with the immune system so that Luke's viral illness provides protection against ed What virakillness caused the lesion on Luke's wrist? smallpox? How does this case illustrate the basis for the development of vaccines and their use in immunization? 3.

Explanation / Answer

1. Cowpox, a viral infection in cows which can spread to humans through contact (zoonosis) has caused illness in Luke.

2. When Luke got cow pox virus , immune system of the body responded by production of antibodies against the virus. The virus closely resembles small pic virus, therefore antibodies in the blood of Luke against cowpox has provided immunity against small pox to Luke.

3. The structure and surface antigens of cowpox and small pic resemble very closely therefore antigens from one virus are used to design vaccine for the other.

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