50) _______When cells begin to migrate in response to signals (e.g. wounding, tu

Question

50) _______When cells begin to migrate in response to signals (e.g. wounding, tumor cell metastasis), they typically free themselves up from their surrounding ECM by secreting matrix degrading enzymes (e.g. MMPs, matrix metalloproteinases). Which of the following are likely substrates for MMP degradation during this response? (1) collagen, (2) basement membrane, (3) transcription factors, (4) microtubules, (5) plasma membrane, or (6) acrosomal vesicle

   a) 4, 5 and 6

   b) 1 and 5

   c) 1 and 6

   d) 2, 3 and 4

   e) 1 and 2

49) _______Which of the following are required for successful fertilization to occur? (1) cortical granule reaction, (2) pronuclear migration (3) cleavage, (4) acrosome reaction, or (5) motile sperm

   a) 1, 2 and 3

   b) 2, 4 and 5

   c) 1, 3 and 4

   d) 4 and 5

   e) 3, 4 and 5

51) _______Which of these statements is true? Integrins are: (1) transmembrane proteins that mediate cell- ECM interactions, (2) transmembrane proteins that mediate cell- cell interactions, (3) nuclear proteins that integrate Wnt and FGF signaling during limb bud initiation, (4) ECM proteins that bind growth factors and morphogens, or (5) ECM proteins involved in cadherin-mediated cell-cell interactions

   a) 1

   b) 2

   c) 3

   d) 4

   e) 5

Explanation / Answer

I believe the correct answers to be

50) E) 1 and 2 because collagen and basal membrane are needed to be degraded for the process to occur.

49) D) 4 and 5 i.e acrosome reaction and motile sperm are needed for fertilization

51) A)1 i.e transmembrane proteins that mediate cell-ECM interactions.

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