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Antibiotics are commonly used to treat bacterial infections, although they must

ID: 213598 • Letter: A

Question

Antibiotics are commonly used to treat bacterial infections, although they must be used carefully due to the risk of antibiotic resistant strains. When H. pylori causes symptoms, it is often treated with a medication to make the stomach less acidic (such as a proton pump inhibitor) and with a combination of antibiotics (using more than one reduces the likelihood that resistance will develop). The chapter describes how the use of oral antibiotics can affect the gut microbiota and contribute to the development of Clostridium difficile infections. Do you think that the use of topical antibiotics on the skin affects the normal skin microbiota? Choose all correct answers. View Available Hint(s) No, because antibiotics do not penetrate the skin, and skin microbes live beneath the upper layers of the epidermis. Yes, because the normal microbiota help to prevent colonization by pathogenic species Yes, because the antibiotics may encourage the growth of antibiotic-resistant species. No, because antibiotics used on the skin are less toxic than those taken orally. Yes, because the microbial communities on the skin and in the gut are very similar in composition. No, because antibiotics only target harmful species and do not harm the normal microbiota. Submit

Explanation / Answer

Yes, because the antibiotics may encourage the growth of antibiotic-resistant species Yes, because the normal microbiota help to prevent colonization by pathogenic species.

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