You have engineered the X chromosome in female mice such that one X chromosome e

Question

You have engineered the X chromosome in female mice such that one X chromosome expresses green fluorescent protein when active, while the other expresses red fluorescent protein. You have used these mice to study cancer in females. You know that each tumor is a clonal cellular proliferation, meaning all of its proliferating cells are decendants of a single original cancer-causing cell. It follows that, unless X-chromosome inactivation is perturbed in tumors... A. all tumors in one mouse should express the same fluorescent protein (either red or green), but tumor cells from different mice can show either red or green fluorescent. B. the cells in any tumor should all express the same fluorescent protein (either red or green), but independently derived tumors in the same mouse can show either green ot red fluorescence. c. different cells within each tumor can express different fluorescent proteins, and the tumors would therefore show yellow fluorescentce, but each cell shows either red it green fluorescence. d. each cell can express both fluorescent proteins and would therefore emit yellow fluorescence, and the tumors woulf glow in yellow as well. e. different tumors would show red, yellow, or green fluorescence.

Explanation / Answer

As, all of its proliferating cells are decendants of a single parent , cancer-causing cell, so they will of same color as that of parent cell either red or the green. Tumor cell will always show either green or either yellow because of the involvement of one parent.

Hence, option A is correct.

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