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6. What is true regarding the abundance of recombinant versus non-recombinant pr

ID: 216808 • Letter: 6

Question

6. What is true regarding the abundance of recombinant versus non-recombinant progeny from AND genetic cross involving two linked genes which have some distance between? 7. An F1 individual with the genotype QqRr results from the following cross: QQRR x qqrr. If this F1 individual is then used in a testcross, and the frequency of recombination (RF) between the linked Q and RIociis 44%, how many individuals out of 500, generated from this test cross should have the genotype QqRr? 8. Physical maps of linked genes based upon the results of 2-point genetic crosses often the distance between two loci that are separated by a large distance due to double crossover events between the two loci which go undetected. 9. If two genes, A and B, are completely independent, a testcross with an individual heterozygous at both loci (AaBb) should yield what phenotypic ratios in the progeny? If the two genes are completely linked (with no recombination), what will the phenotypic ratios in the progeny be?

Explanation / Answer

6.

The answer is the recombinants and non recombinants (parental categories) are varies in their aboundance. The recombinant categories are low in frequency where as the non recombinant categories are high in freequency.

7.

The map distance = % of recombinantion.
The total offspring (100%) = % of parental categories + % of the recombinant categories.
So, the % of parental categories = The total offspring (100%) - % of the recombinant categories.

For QR genes,

The map distance = % of recombinantion = 44%

% of parental categories = 100 - 44 = 56.

As each category contains two genotypes, the % of individual genotypes are

% of individual parental categories = 56/ 2 = 28% or 28/100
% of individual recombinant categories= 44/ 2 = 22% or 22/100.

So, the % of genotypes from this cross =

Parenal categories =
QR/qr = 28% or 28/100
qr/qr = 28% or 28/100

Recombinant categories =
Qr/qr = 22% or 22/100
qR/qr = 22%. or 22/100

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