2. Broad-spectrum drugs that disrupt the body\'s normal flora often cause a. Nep
ID: 217289 • Letter: 2
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2. Broad-spectrum drugs that disrupt the body's normal flora often cause a. Nephrotoxicity b. Superinfections c. Allergic reactions d. Drug toxicity e. All of the above 3. A chemical that inhibits penicillinase (beta-lactamase) is a. Synercid b. Aztreonam c. Imipenem d. Methicillin e. Clavulanic acid 4. Which of the following antibiotics is used to treat tuberculosis? a. Penicillin G b. Vancomycin c. Aminoglycosides d. Isoniazid e. Amphotericin Which of the following types of antimicrobial drugs makes the microbe more susceptible to osmotic pressure? 5. a. Drugs that inhibit nucleic acid synthesis b. Drugs that inhibit cell wall synthesis c. Drugs that inhibit protein synthesis d. Drugs that inhibit metabolic pathways e. None of the above Which of the following is not true of the inhibition observed in a Kirby-Baue test? 6. a. It is measured as a diameter b. The larger the zone, the more resistant the organism is c. It is a clearing zone with no growth d. It is the result of diffusion of the drug out of the paper diskExplanation / Answer
2. b. Superinfections
Since normal flora is disrupted, the patient is more prone to infection by another pathogen which is not affected by the broad spectrum drug.
3. e. Clavulanic acid
Clavulanic acid can break beta-lactam ring and.
4. d. Isoniazid
This drug inhibits synthesis of mycolic acid, an important component of their cell wall.
5. b. Drugs that inhibit cell wall synthesis
Drugs that inhibit cell wall synthesis make the microbes more susceptible to osmotic pressure. Due to lack of cell wall, osmosis cannot take place.
6. b. The larger the zone, the more resistant the organism is.
The larger the zone, the more susceptible the organism is.
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