Tumor invasion requires all of the following except 1)loss of cellular adhesion

Question

Tumor invasion requires all of the following except 1)loss of cellular adhesion 2) translocation of cells 3) lysis of extra cellular matrix proteins 4) cell migration 5) all of the above Tumor invasion requires all of the following except 1)loss of cellular adhesion 2) translocation of cells 3) lysis of extra cellular matrix proteins 4) cell migration 5) all of the above 1)loss of cellular adhesion 2) translocation of cells 3) lysis of extra cellular matrix proteins 4) cell migration 5) all of the above

Explanation / Answer

Ans- all of the above

Involving following steps-detachment from primary tumour or loss of cellular adhesion so that can easily spread.

Function as adhesive substrate, tumour cell proliferation and spread to other parts of body and penetration of small lymphatic and vascular channels.

Tumour cell migration and intravasion into the circulation.

Tumour cell dissemination along chemokine gradient,

Extravasion to secondary site and tumour cell proliferation and colonisation, myeloid and endothelium cell recruitment.

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