QUESTION 3 10 points Save Answer How do microglia impact neuronal function? They

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QUESTION 3 10 points Save Answer How do microglia impact neuronal function? They decrease the rate of firing and increase synaptic adhesion molecules They decrease the rate of firing and decrease synaptic adhesion molecules O They decrease the number of synapses and increase synaptic adhesion molecules They increase the rate of firing and increase synapse numbers QUESTION 4 10 points Save Answer Which repair mechanism does not occur in mammals when nervous tissue is damaged? Long-range regrowth of damaged axons in the central nervous system Restoration of damaged central neurons Neurogenesis Long-range regrowth of damaged axons in the peripheral nervous system

Explanation / Answer

Ans. 3).Microglia are cells of central nervous system (CNS) that help in immune responses associated with the CNS. Microglia impact neuronal function by decreasing the firing rate of neurons and decreasing the synaptic adhesion molecules. In healthy people, microglia show increased levels of neuronal activity and decrease their firing rate. Addition of microglial cells to culture neuronal cells also decreases the level of synaptic adhesion molecules. Hence, the option " they decrease the rate of firing and decrease synaptic adhesion molecules" is correct answer.  

4). In mammals, three types of neuronal repairs include nuerogeesis, restoration of damaged central neurons, and regrowth ofdamaged axons in the PNS (peripheral nervous system).Repair of damaged axons of central nervous system is limited in mammals, It occurs because of the ectracellular environment and inhibitory effects of glial cells. Hence, the option "long -range regrowth of damaged axons in the central nervous system" is the correct answer.

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