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Genome-wide association studies (GWAS) are used to identify potential genetic va

ID: 219056 • Letter: G

Question

Genome-wide association studies (GWAS) are used to identify potential genetic variants that are associated with traits or diseases. GWAS can either be conducted using marker-based or whole- genome sequences. Genetic researchers may choose one approach over the other. Match the research benefits as pertaining to marker-based, whole-genome, or both approaches. Whole-genome Both Marker-based acceptable for biochemical identifies rare alleles for pathway to remain unknown a disease in a population identifies genes that contribute to uncharacterized diseases allows for large sample sizes with a limited budget

Explanation / Answer

Whole genome sequencing-

Whole-genome Both Marker-based Identifies genes that contribute to uncharacterized disease Identifies rare alleles for a disease in a population Allows for large sample sizes with limited budget Acceptable for biochemical pathway to remain unknown
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