What happens to cardiac derived stem cells when you place them on a decellulariz
ID: 219255 • Letter: W
Question
What happens to cardiac derived stem cells when you place them on a decellularized liver ECM?
a)
They cannot adhere to the matrix as they are not expressing the correct integrins
b)
They die, extracellular matrix alone cannot support cellular differentiation, it provides structure to the cell
c)
They begin expressing liver genes
d)
They remain as cardiac stem cells, as the liver ECM does not have the proper signals to differentiate heart cells
a)
They cannot adhere to the matrix as they are not expressing the correct integrins
b)
They die, extracellular matrix alone cannot support cellular differentiation, it provides structure to the cell
c)
They begin expressing liver genes
d)
They remain as cardiac stem cells, as the liver ECM does not have the proper signals to differentiate heart cells
Explanation / Answer
Answer-
c)
They begin expressing liver genes
As liver ECM has the potential to maintain and guide hepatocyte cell lineages. A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass. These cells are involved in: Protein synthesis.
c)
They begin expressing liver genes
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