The following protein is responsible for the disruption of hydrogen bonding and

Question

The following protein is responsible for the disruption of hydrogen bonding and base stacking during the initiation of DNA replication a) DNA gyrase b) DNA Polymerase III c) Single-stranded DNA binding protein d) sigma (sigma) factor e) DNA helicase The following enzyme is responsible for resolving supercoiling ahead of the DNA replication fork a) DNA ligase b) DNA gyrase c) Single-stranded DNA binding protein d) DNA helicase e) DNA Pol III AZT (shown across), used in treating HIV/AIDS, is an effective inhibitor of nucleic acid synthesis primarily because a) It has an 3' azido nitrogen group instead of a 3' OH b) It is a 2', 3' dideoxy compound

Explanation / Answer

24)Answer is option e.

DNA gyrase open or relaxes the supercoiling of DNA.

So,option a is not correct.

DNA polymerase lll is used in replication either for polymerization or proofreading.

So,option b is not correct.

Single strand binding protein helps in maintaining the structure of replicatiin fork.

So,option c is not correct.

Sigma factor is associated with initiation of transcription.

So,option d is not correct.

As DNA helicase disrupt the hydrogen bonding and base stacking then the strand opens up.

Hence,option e is correct.

25)Answer is option b.

DNA ligase joins the okazaki fragments.

So option a is not correct.

Single strand binding proteins helps in maintaining the structure of replication fork.

So,option c is not correct.

DNA helicase opens the DNA helix but not the supercoiling structure.

So option d is not correct.

DNA pol lll does not help in relaxing the superhelical structure.

So,option e is not correct.

DNA gyrase helps in relaxing the supercoiling structure.

Hence,option b is correct.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.