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If the blood pH is stable at 7.4, then: a. What is the percent saturation of Hb,

ID: 227197 • Letter: I

Question

If the blood pH is stable at 7.4, then: a. What is the percent saturation of Hb, (hemoglobin) in the blood as it leaves the lungs? b. What is the percent saturation of Hb, in the blood as it leaves the tissues? If the blood pH is stable but slightly alkaline at 7.6, then: a. What is the percent saturation of Hb, (hemoglobin) in the blood as it leaves the lungs? b. What is the percent saturation of Hb, in the blood as it leaves the tissues? What percentage of hemoglobin unloaded oxygen as it passed through the tissues? In other words, what is the difference in Hb-saturation before vs, after the blood passed through the tissues? a. At pH 7.4? b. At pH 7.6?

Explanation / Answer

The partial pressure of oxygen in the alveoli (i.e. arterial blood) is 100mm of Hg and that in the venous blood is 40mm of Hg.

With this information, we can now refer the graph and find out the answers to the question.

Answer 1a: 96% saturation of Hemoglobin (where the 7.4 line touches the 100mm Hg)

Answer 1b: 75% saturation of Hemoglobin (where the 7.4 line touches the 40mm Hg)

Answer 2a: 100% saturation of Hemoglobin (where the 7.6 line touches the 100mm Hg)

Answer 2b: 83% saturation of Hemoglobin (where the 7.6 line touches the 40mm Hg)

Answer 3a: At Ph 7.4, difference in saturation of Hemoglobin is 100 – 83 = 17%

Answer 3b: At Ph 7.6, difference in saturation of Hemoglobin is 96 – 75 = 21%

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