In a prospective study of depression and dementia, you recruit participants who

Question

In a prospective study of depression and dementia, you recruit participants who are between ages 65 and 75 and not suffering dementia. At intake, you give them a screening test for depression. Five years later, you give them the Mini Mental State Examination, which assesses cognitive function. There is no loss to follow-­up. Your observed risk ratio is 2.40: elderly people who are depressed have 2.40 times the risk of dementia compared with elderly people who are not depressed over 5 years. If, instead of perfect follow-­up, you ended up with 20% fewer participants after 5 years. It turns out that depressed people were more likely to drop out than non-­depressed. What would the effect be on your risk ratio?

Explanation / Answer

Assuming that the depressed is 20 percnt then accoding to ratio of depressed / normal which is 240/100 calculate the drop n depressed people which is 340 *20/ 100 ( total people is 340) Hence 68 people did not take part. Acc to data these are demntia people . So drop will be from demetia . Hence the total of depresed will fall to 240 - 68 = 172. But other memebers are 100 hence the ratio would drop to 172/100 which is 1.72

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