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8. The graph below comes from data collected by researchers trying to understand

ID: 245090 • Letter: 8

Question

8. The graph below comes from data collected by researchers trying to understand how respiration is regulated. The scientists had unanesthetized goats breathe air with differing amounts of CO2 and measured the alveolar ventilation of the goats. Some of the data they collected is shown below. Normal air contains about 0.03% co2. 14 1 E 12 10 0.03 CO2 concentration of inspired air (%) Figure 1- Effect of the composition of inspired air on alveolar ventilation in unanesthetized goats (n-6). Data taken from Table 4 in Pappenheimer, J.R., V. Fencl, S.R. Heisey, and D. Held (1965). Am. J. Physiol 208(3):436-450 Based on what we think we know about the regulation of respiration, explain the data they obtained (i.e. explain the increased ventilation). Your answer should include mention of the sensory neurons involved, their location, and the "control unit" involved. You should also mention the links between the composition of air inspired and what is actually being measured by the sensory neurons.(5 points)

Explanation / Answer

Regulation of respiration :-

Respiration is the process of gaseous exchange between the environment and the cell and tissues of a human body via lungs .

Respiration is of two types :-internal respiration:-exchange of gases from the blood and the Body tissues.

external respiration :- exchange of gases from lung tissues to blood .

Ventilation :- it means movement of air between the environment and the lung via the process of inhalation and exhalation.

regulisation of respiration is done by chemo receptors that are present on the CSF lining of central nervous system and in peripheral nervous system on the arch of aorta and carotid artery whenever concentration of carbon dioxide increases signals from these chemoreceptors will go to our brain and brain will send the signal to our diaphragm and intercostal muscles via Phrenic and the vagus nerve and increase the respiration.

Other then these chemoreceptors there are some other receptors also present in our brain for inspiration and expiration these are present in medula oblangata and pons

Centers that are present in medula oblangata controls the rate and depth of respiration while the apenuestic and pneumotoxic center present in pons control the rythem of respiration.

Concentration of co2 Is directly proportional to alveolar ventilation and rate of

respiration.

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